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DOI: https://doi.org/10.31071/kit2020.16.09


Inventory reference

ISSN 1812-7231 Klin.inform.telemed. Volume 15, Issue 16, 2020, Pages 88-98


Author(s)

N. O. Shushliapina, A. V. Lupyr, O. O. Taranukha, O. E. Cherniakova


Institution(s)

Kharkiv National Medical University, Ukraine


Article title

Clinical significance of bulbar conjunctive vessel biomicroscopy in patients with pathology of intranisal structures and nasal breathing disoders


Abstract (resume)

Introduction. The clinical significance of biomicroscopy of bulbar conjunctival vessels in patients with pathology of intranasal structures and nasal breathing disorders was considered. The study of the clinical anatomy of the vascular system is very important in otorhinolaryngology. The conjunctiva of the eye, like the nasal cavity, is supplied with blood from the external and internal carotid arteries. Therefore, the assessment of biomicroscopy of the bulbar conjunctiva can be considered the only functional reflection of microcirculation not only at the level of the body as a whole, but also the nasal cavity in particular. The study of the microcirculation of the bulbar conjunctiva allows us to assess the biomedical indicators of the state of trophic capabilities with more information than in the study of individual human organs and tissues.

Aim. Evaluation of the clinical significance of bulbar conjunctiva microcirculation in patients with pathology of intranasal structures and nasal breathing disorders.

Results. Our study showed that in patients with changes in intranasal structures and nasal breathing disorders conjunctival biomicroscopy is characterized by the peculiarities of a number of morphostructural parameters of the microcirculatory tract, despite the nonspecificity of vascular disorders. With increasing magnitude of nasal resistance and duration of the disease, microcirculatory (MC) disorders from functional changes to the appearance of morphological disorders of both vascular and intravascular units of the MC channel intensified. An unfavorable manifestation of which was a decrease in the number of functioning capillaries and the appearance of perivascular disorders.

Conclusions. Our conclusions coincide with the data of other authors. It should be noted that biomicroscopy of the bulbar conjunctiva is absolutely justified and allows to assess the structures of microcirculation in terms of functional disorders. However, this method, against the background of obvious advantages, has disadvantages, such as complexity of image stabilization (because of the eyeball's movements), the lack of assessment of the perivascular space, the inability to study the transitional capillary. The prospect of work is to conduct capillaroscopic studies directly in the mucous membrane of the nasal cavity to find direct correlations between microcirculation in the study area and peripheral areas.


Keywords

Microcirculation, Bulbar conjunctiva, Nasal breathing disorders, Intranasal structures


References

1. Dzeman M. I. Sleep apnea syndrome. Praktykuyuchyy likar [J. Practitioner], 2013, № 4, pp. 74–77.

2. Feschenko Yu. I., Yashina L. A. Obstructive sleep apneahypopnea syndrome is an important general therapeutic problem. Zdorov'ya Ukrainy [Health of Ukraine], 2008, v. 22, No. 1, pp. 8–9. (In Russ.).

3. Wewers M. E., Lowe N. K. A critical review of visual analogue scales in the measurement of clinical phenomena. Research in Nursing and Health, 1990, vol. 13. pp. 227–236.
https://doi.org/10.1002/nur.4770130405

4. Bezshapochny S. B., Avrunin O. G., Loburets V. V., Loburets A. V., Gasyuk Yu. A. Prediction of functional results of septoplasty. Otorynolarynholohiya [J. Otorhinolaryngology], 2020, vol. 3, № 4, pp. 67–72. (In Ukr.).
https://doi.org/10.37219/2528-8253-2020-4-67

5. Passali D. et al. Nasal decongestants in the treatment of chronic nasal obstruction: efficacy and safety оf use. Expert Opinion of Drug Safety, 2006, vol. 6, no. 5, pp. 783–790.
https://doi.org/10.1517/14740338.5.6.783

6. Belogolovov N. V. To the question of the effect of obstructed nasal breathing on blood morphology and oxidative processes. Abstract of the dissert. of the cand. of med. Sci., 1903, 87 p., SPb, 1903, 87 p. (In Russ.).

7. Golubev H. A. Changes in the functional state of the cerebral cortex in patients with chronic diseases of the nose and its paranasal sinuses. Vestnik Otorinolaringologii [Bulletin of Otorhinolaryngology], 1959. No. 2, pp. 15–22. (In Russ.).

8. Kryukov A. I., Hardov M. V., Sekerina A. O. Effect of chronic nasal obstruction on cerebral blood flow and blood oxygenation. Proc. of the XI Congress of Otorhinolaryngologists "Science and Practice of Otorhinolaryngology", 2012, p. 177. (In Russ.).

9. Kryukov A. I., Hardov M. V., Sekerina A. O. Chronic obstruction of nasal breathing: the effect of duration of suffering on cerebral blood flow. Funktsional'naya diagnostika [Functional diagnostics], 2012, no. 4, pp. 56–60. (In Russ.).

10. Schranz D. Pulmonale Hypertension im Kindes — und Jugendalter. Monatsschr Kinderheilkd, 2003, iss. 151, pp. 424–441.
https://doi.org/10.1007/s00112-002-0545-5

11. Shushlyapina N. O. Analysis of the state of microcirculation in patients with pathology of intranasal structures in respiratory and olfactory disorders. Fotobiolohiya ta fotomedytsyna [J. Photobiology and Photomedicine], 2019, № 28, p. 54–61. (In Ukr).
https://doi.org/10.26565/2076-0612-2019-28-06

12. Safonova T. N., Lutsevich E. E., Kintyukhina N. P. Changes in the microcirculation of the bulbar conjunctiva in various diseases. Vestnik Oftal'mologii [Bulletin of Ophthalmology], 2016, no. 2, pp. 90–95. (In Russ.).
https://doi.org/10.17116/oftalma2016132290-95

13. Kozlov V. I. Kapillyaroskopiya v klinicheskoy praktike [Capillaroscopy in clinical practice]. M., Practical Medicine Publ., 2015, 232 p. (In Russ.).

14. Timoshchuk O. V. Possibility of diagnostics for microcirculation in children with chronic gastroduodenitis in a general aspect. Mizhnarodnyy zhurnal pediatriyi, akusherstva ta hinekolohiyi [Intern. J. Pediatrics, Obstetrics and Gynecology], 2016, vol. 10, no. 2–3, pp. 24–28. (In Ukr.).

15. Bogoyavlenskaya O. V., Oslopov V. N. Study of the state of the microcirculation system in arterial hypertension. Prakticheskaya meditsina [Practical Medicine], 2010, vol. 5, no. 44, pp. 116–118. (In Russ.).

16. Kuzmichev, A. Ya. Printsipy klinicheskoy kapillyaroskopii [Principles of clinical capillaroscopy]. Kiev, 1965, 170 p. (In Russ.).

17. Pokrovsky A. V. Klinicheskaya angiologiya [Clinical angiology]. M., Medicine Publ., 2004, 1700 p. (In Russ.).

18. Malaya L. T., Vlasenko M. A., Miklyaev I. Yu. and other Myocardial infarction. Vrachebnoye delo [Medicine], 1975, no. 2, pp. 21–25. (In Russ.).

19. Ivanov K. P. Modern Medical Problems of Microcirculation and Hypoxic Syndrome. Vestnik Rossiiskoi Akad. Med. Nauk [Annals of the Russ. Academy of Med. Sci.], 2014, iss. 1–2, pp. 57–63. (In Russ.).
https://doi.org/10.15690/vramn.v69.i1-2.943

20. Chernukh A. M., Alexandrov P. N., Alekseev O. V. Mikrotsirkulyatsiya [Microcirculation], 2nd ed., M., Medicine Publ., 1984, 432 p. (In Russ.).

21. Vereshchak V. V., Sidorov N. M., Kalyuzhna L. D. Clinical methods of research of a hemomicrocirculatory channel. Method. recommend. Nat. Med. Acad. Postgraduate Education named after P. L. Shupik, K., Nauk. Dumka Publ., 2008. 43 p. (In Ukr.).

22. Tymoschuk V. Possibilities of diagnosing the state of microcirculation in children with chronic gastroduodenitis in the age aspect. Mizhnarodnyy zhurnal pediatriyi, akusherstva ta hinekolohiyi [Intern. J. Pediatrics, Obstetrics and Gynecology], 2016, vol. 10, № 2-3, pp. 24–28. (In Ukr.).

23. Kovaleva A. A., Avrunin O. G. Possibilities of microcirculation assessment by capillaroscopy. |Proc. IV Intern. Scientific-practical Conf. "Transport safety — the basis of effective infrastructure: problems and prospects", Kharkiv, KhNADU, 2019, p. 231–233. (In Ukr.).

24. Kovaleva A. A., Khudayeva S. A., Shushlyapina N. O., Avrunin O. G. Development of a computer system for the detection of hemomicrocirculation disorders. Proc. Scientific-practical Conf. with International Particip. "Current issues of clinical and industrial transfusiology", Kharkiv, 2019, p. 17. (In Ukr.).

25. Sayfullina F.R. Microcirculation in health and disease. Al'ternativnaya meditsina [Alternative medicine], 2010, vol. 18, no. 1, pp. 9–16. (In Russ.).

26. Obukhova M. P., Valeeva E. T., Volgareva A. D., Galimov R. R., Gimranova G. G. Analysis of the results of studying hemomicrocirculation in persons exposed to various industrial factors. Permskiy med. Zhurnal [Perm. Medical J.], 2016, vol. XXXIII, no. 4, pp. 94–101. (In Russ.).

27. Bezditko P. A., Panchenko M. V., Durasta I. G. etc. Diseases of the conjunctiva. Methodical instructions for students and interns, Kharkiv, KhNMU, 2018, 24 p. (In Ukr.).

28. Kovalova A., Shushliapina N., Avrunin O., Zlepko A. et al. Possibilities of automated image processing at optical capillaroscopy. Proceedings of SPIE, 2020, p. 11456.
https://doi.org/10.1117/12.2569772


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