DOI:

Inventory reference

ISSN 1812-7231 Klin.inform.telemed. Volume 16, Issue 17, 2021, Pages 00-00

Author(s)

Shushlyapina N.O., Gorgol N.I., Ibrahim Yunuss Abdelhamid, Nosova Ya.V.

Institution(s)

Kharkiv National Medical University

Article title

Features of rhinocytograms in patients with respiratory-olfactory disorders

Abstract (resume)

Introduction. The peculiarities of rhinocytogram in patients with pathology of intranasal structures with respiratory-olfactory disorders were considered in the work. The study of cytological examination of the mucosa of various organs, in particular, the nasal cavity and paranasal sinuses is of paramount importance in otorhinolaryngology and is a non-invasive diagnostic method. It allows the doctor to determine the composition and amount of cellular elements in the material and assess their condition (destruction, proliferation, dystrophy, necrosis, etc.), to determine the intensity of the body's reactive abilities, to monitor the dynamics of organ renewal or healing.

Purpose of work. To analyze the features of the rhinocytogram in patients with pathology of intranasal structures with respiratory-olfactory disorders.

Results. In patients with pathology of intranasal structures with respiratory-olfactory disorders, depending on the degree of obstruction of the nasal cavity revealed features of the structure and number of cells of the respiratory epithelium, which indicated an inflammatory process. Some changes in the form of cilia detachment, vacuolation of the cytoplasm, karyopyknosis, karyorexis, karyolysis, bare nuclei, uneven contour of the cytoplasm reflected dystrophic changes of the ciliated epithelium. In addition, basal epitheliocytes, which are poorly differentiated cells involved in epithelial regeneration, have also been observed among epithelial cells. The presence of a large number of these cells in the smears indicated a violation of trophic and mechanical function of CO, weakening of intercellular and epithelial-mesenchymal combinations, responsible for both the integrity of intercellular contacts and the fixation of epitheliocytes on the basement membrane. As a result of such events there is a slight injury of the epithelium, which causes severe desquamation of basal cells. The rhinocytogram showed mucus, as well as bacterial and fungal contamination, which was a consequence of impaired protective function of the mucosa.

Conclusions. It should be noted that in the study of cytological drugs, namely depending on the degree of obstruction of the nasal cavity in patients with respiratory olfactory disorders is determined by the predominance of certain cell types with inflammatory elements and microorganisms, which is assessed as inflammatory (acute-inflammatory, chronic inflammatory, chronic-inflammatory with exacerbation), desquamative, atrophic process.

Keywords

rhinocytograms, respiratory-olfactory disorders, mucous membrane

References

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