Українська  English  Русский  


Inventory reference

ISSN 1812-7231 Klin.inform.telemed. Volume 11, Issue 12, 2015, Pages 63–68


O. Antonchyk, A. Jadooei, V. Shulgin


National Aerospace University named after N. Ye. Zhukovsky, Kharkiv, Ukraine

Article title

Algorithm of cuffless blood pressure estimation based on maximum likelihood method

Abstract (resume)

Introduction. Continuous monitoring of blood pressure (BP) is one of the most essential problems in preventive medicine. Its implementation is complicated since there are no simple and comfortable for patient methods of continuous BP monitoring.

The object of the study is to develop an algorithm and assess the accuracy of indirect cuffless BP measurement based on joint processing of different functional characteristics of human cardiovascular system.

Formulation and solution of the problem. Using relations of different characteristics of human cardiovascular system an algorithms of systolic and diastolic BP estimation by measuring pulse transit time (PTT) and heart rate (HR) based on maximum likelihood method have been developed.

Results. Performed series of experiments showed that developed algorithms were efficient and accurate.

Conclusion. The feasibility of continuous cuffless BP measurement based on joint processing of such characteristics of human cardiovascular system as PTT and HR is shown. An algorithm for BP measurement based on maximum likelihood method with accuracy that satisfies BHS and ANSI/AAMI requirements have been developed.


Cuffless BP measurement, Pulse transit time, PTT, Electrocardiogram, ECG, Maximum likelihood estimation, MLE


1. Federico S., Harinath Garudadri. Noninvasive Cuffless Estimation of Blood Pressure from Pulse Arrival Time and Heart Rate with Adaptive Calibration. in Proc. IEEE BSN Conf., Cambridge, 2009, pp. 114–115.

2. Soo-young Ye, Gi-Ryon Kim, Dong-Keun Jung, Seong-wan Baik, Gye-rok Jeon. Estimation of Systolic and Diastolic Pressure using the Pulse Transit Time, J. World Academy of Science, Engineering and Technology, 2010, vol. 43, pp.726–731.

3. Heiko Gesche, Detlef Grosskurth, Gert Kuchler. Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method. J. J. Appl. Physiol., 2011, pp. 726–731.

4 Shulgin V. I., Jadooei Ali, Shulga D. I., Nasedkin K. V., Fedotenko V. V. Izmerenie arterialnogo davleniya na osnove sovmestnoy obrabotki nabora fiziologicheskih pokazateley [Measurement of arterial blood pressure, on the basis of co-processing of a set of physiological parameters], Klinicheskaya informatika i Telemeditsina [Clinical informatics and Telemedicine], 2012, vol. 8, iss. 9, pp.45–50. (in Russ.)

5 Shulgin V. I., Jadooei Ali, Zaderykhin O. K. Adaptive calibration of blood pressure measurer based on pulse time transit estimation. in Proc. International Scientific Conference ICTM-2012, November 27–30, 2012. Kharkiv, Ukraine (in Russ.)

6. Jadooei Ali, Zaderykhin O., Shulgin V. I. Adaptive Algorithm for Continuous Monitoring of Blood Pressure Using a Pulse Transit Time. XXXIII International Scientific Conference Electronics and Nanotechnology in Proc. IEEE, April 16–19, 2013. Kyiv, Ukraine, pp. 297–301.

Full-text version