DOI: https://doi.org/10.31071/kit2020.16.07 Inventory reference ISSN 1812-7231 Klin.inform.telemed. Volume 15, Issue 16, 2020, Pages 15-27 Author(s) V. N. Sokolov, L. V. Anischenko, A. S. Byanov, O. V. Nikitina Institution(s) Odessa National Medical University, Ukraine Article title Community acquired pneumonia. Differential diagnosis. COVID-19 Abstract (resume) Introduction. The paper presents the results of X-ray examination of patients with lung lesions caused by diseases and computed tomography (CT) of patients with COVID-19 of varying degrees of infiltration according to the categorical CT scheme from CO-RADS 1 to CO-RADS 6, developed by the Dutch Radiological Society (NVvR). Good results can be achieved by detecting the early stage of the disease in COVID-19. The work considers indications, contraindications, methodology and interpretation, at different phases of infiltration in COVID-19. Objective. To review the dynamic models of CT imaging of lungs affected by COVID-19, to define CT character of primary and postprimary infection and discuss the role of imaging in differential diagnostics and monitoring of the pathology. Materials and research methods. 85 patients (the median of 48 y.o. to the 17 to 84 y.o. range) were examined. All patients underwent CT procedure ("Toshiba Corp." 64-sl. CT). Results. At an early stage bilateral basal peripheral changes of the "ground glass" type opacity, generally of minuscule area, predominate which precurse development of viral pneumonia in COVID-19. As the disease progresses areas of change in the tissue appear patterned according to the type of "patchwork", consolidation areas form resembling OP "reverse halo". Complete resorption of changes in lungs is likely. Resolution of pathological changes could be observed after a month and longer with a successful outcome. Conclusion. At the stage of the outbreak progression the role of CT imaging methods in assessing the condition of lungs could not be overestimated. They provide means to identify changes at the subclinical stage, to assess the severity of the course and conduct differential diagnostics, but also to inform about the likelihood of COVID-19 when PCR testing results are lacking. The role of CT is indeed prevailing in clinical conditions of limited resources and while coping with a large patient cohort with acute respiratory diseases of undefined aetiology. Keywords Differential diagnosis, CT examination, COVID-19, CO-RADS scheme References 1. Dvoretsky L. I. Outside hospital-acquired pneumonia in the elderly. Antibiotic therapy strategy and tactics. Pul'monologiya [Pulmonology], 2001, no. 4, pp. 91–95. (In Russ.). 2. Kotlyarov P. M. Radiation diagnosis of acute pneumonia in clinical practice. Pul'monologiya [Pulmonology], 1997, no. 1, pp. 7–13. (In Russ.). 3. Lapteva I. M. Atypicalpneumonia. Zdravookhraneniye [Health care], 1999, no. 11, pp. 55–56. (In Russ.). 4. Lapteva I. M. Modern approaches to the diagnosis and treatment of atypical pneumonia. Meditsinskiye novosti [Medical News], 2000, no. 2, pp. 44–45. (In Russ.). 5. Mikhailov A. N. Rentgenosemiotika i diagnostika bolezney cheloveka [X-ray semiotics and diagnostics of human diseases]. Ministry of Higher Education Publ., 1989, 608 p. 6. Mikhailov A. N. Rukovodstvo po meditsinskoy vizualizatsii [Medical Imaging Guide], Ministry of Higher Education Publ., 1996, 506 p. (In Russ.). 7. Pneumonia: an urgent problem of medicine (round table). Pul'monologiya [Pulmonology], 1997, no. 1, pp. 75–91. (In Russ.). 8. Tyurin I. E., Ivanishak B. E. The value of computed tomography in the differential diagnosis of infiltrative changes in the lungs. Vestnik rentgenologii i radiologii [Bulletin of radiology and radiology], 1998, no. 2, pp. 38–51. (In Russ.). 9. Fedchenko G. G., Chernehovskaya N. E., Rannev I. B. Radiation and endoscopic diagnostics of pneumonia. Vestnik rentgenologii i radiologii [Bulletin of X-ray and radiology], 2002, no. 1, pp. 21–26. (In Russ.). 10. Chuchalin L. G. Pneumonia is an urgent problem in medicine. Terapevticheskiy arkhiv [Therapeutic archive], 1995, no. 3, pp. 3–7. (In Russ.). 11. Sokolov V. N., Feschenko Yu. I., Perelman M. I., Stepula V. V., Shandra A. A. and oth. Pul'monologiya [Pulmonology]. Reference manual. Ed. prof. Sokolov V. N., 1998, 364 p. (In Russ.). 12. Yudin A. L., Afanasyeva N. I., Abovich Yu. A., Romanova E. A. Radiation diagnosis of diffuse infiltrative lung diseases (review). Radiologiya-praktika [J. Radiology-practice], VIDAR-M Publ., 2000, no. 2, pp. 10–17. (In Russ.). 13. Morozov S. P., Vladzimirsky A. V., Ledikhova N. V. Telemedicine technologies (teleradiology) in the service of radiation diagnostics. Series "Best Practices of Radiation and Instrumental Diagnostics", 2018, 72 p. (In Russ.). 14. Nikiforov V. V., Suranova T. G., Mironov A. Yu., Zabozlaev F. G. New coronavirus infection (COVID-19): etiology, epidemiology, clinic, diagnosis, treatment and prevention. Study guide, Moscow, 2020, 48 p. (In Russ.). 15. Prevention, diagnosis and treatment of new coronavirus infection (2019-nCoV). Temporary guidelines of the Ministry of Health of the Russian Federation. Version 6 (28.04.2020). (In Russ.). 16. Shlemskaya V.V., Khateev A.V., Prosin V.I., et al. New coronavirus infection COVID-19: a brief description and measures to counter its spread in the Russian Federation. Meditsina katastrof [Disaster medicine], 2020, no. 1, pp. 57–61. (In Russ.). 17. Tao Ai, Zhenlu Yang, HongyanHou, Chenao Zhan, and oth. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases, Radiology, 2020, vol. 296, no. 2, pp. E32-E40. 18. Canadian Society of Thoracic Radiology and Canadian Association of Radiologists' Statement on COVID-19. 19. Prokop M., van Everdingen W., Tjalco van Rees V. et al., and oth. CO-RADS: A Categorical CT Assessment Scheme for Patients Suspected of Having COVID-19—Definition and Evaluation. Radiology, 2020; iss. 296, pp. E97–E104. 20. Wei-Cai Dai, Han-Wen Zhang, Juan Yu, et al. CT Imaging and Differential Diagnosis of COVID-19. Can. Assoc. Radiol. J., 2020, vol. 71, no. 2, pp. 195–200. 21. Fang Y., Zhang H., Xie J., et al. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology, 2020. vol. 296, no. 2, pp. E115–E117. 22. Wei-jie Guan, Zheng-yi Ni, Yu Hu, et al. China Medical Treat-ment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N. Engl. J. Med., 2020, iss. 382, pp. 1708–1720. 23. Hansell D. M., Bankier A. A., MacMahon H., et al. Fleischner Society: Glossary of terms for thoracic imaging. Radiology, 2008, vol. 246, iss. 3, pp. 697–772. 24. Avdeev S., Avdeeva O., Chuchalin A. Obliterating bronchiolitis. Russkiy meditsinskiy zhurnal [Russian medical journal], 1998, no. 4, p. 2. (In Russ.) 25. Belovol A., Kniazkova I., Shapovalova L. Wegener granulomatosis (granulomatosis with polyangitis). ZH. Praktychna Anhiolohiya [J. Practical Angiology], 2012, no. 1–2, iss. 50–51, pp. 27–36. (In Ukr.). 26. Gavrysiuk V., Multiple cystic lung diseases. Ukr. pul'monolohichnyy zhurnal [Ukr. J. Pulmonology], 2019, no. 3, pp. 58–67. (In Ukr.). 27. Delektorskaya V. Neuroendocrine lung tumors: modern classification and morphologic diagnosis. ZH. Uspekhi molekulyarnoy diagnostiki [J. Advances of molecular diagnostics], 2017, vol. 4, no. 2, pp. 46–58. (In Russ.). 28. Chuchalin A., ed. Pul'monologiya. Natsional'noye rukovodstvo [Pulmonology: National guidelines]. Short edition, М., GEOTAR-Media Publ., 2020, 800 p. (In Russ.). Full-text version http://kit-journal.com.ua/en/viewer_en.html?doc/2020_16/007.pdf |
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